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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3HC1
All Species:
19.39
Human Site:
T446
Identified Species:
38.79
UniProt:
Q86WB0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WB0
NP_057562.3
502
55262
T446
E
S
R
E
N
G
G
T
E
P
D
A
S
A
P
Chimpanzee
Pan troglodytes
XP_001156206
502
55199
T446
E
S
R
E
N
G
G
T
E
P
D
A
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001094530
502
55199
T446
E
S
R
E
N
G
G
T
E
P
D
A
S
A
P
Dog
Lupus familis
XP_532428
589
65257
T533
E
T
R
E
H
G
G
T
E
T
D
A
S
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80YV2
501
55178
T445
E
T
K
E
N
G
E
T
E
V
D
A
C
T
P
Rat
Rattus norvegicus
NP_001120765
501
55306
T445
E
T
K
E
N
G
K
T
E
V
E
A
C
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510194
625
67731
D506
D
V
Q
E
S
S
R
D
E
S
D
V
C
T
A
Chicken
Gallus gallus
XP_414975
484
53210
D428
E
G
G
E
T
P
E
D
P
E
K
E
P
A
K
Frog
Xenopus laevis
Q6P7H4
477
53273
E421
G
T
N
T
M
G
S
E
I
Q
E
E
A
R
R
Zebra Danio
Brachydanio rerio
NP_001070846
492
54140
F434
D
N
Q
D
A
S
D
F
V
G
C
E
A
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200598
300
33790
P245
E
E
H
R
S
W
C
P
W
T
K
P
A
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141693
698
76497
L560
A
D
A
D
Q
H
G
L
E
P
R
F
C
S
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
79.2
N.A.
85
85.8
N.A.
53.4
62.3
52.1
43
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.1
99
81.4
N.A.
91
91.2
N.A.
63.3
74.5
65.3
61.9
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
100
100
100
66.6
N.A.
60
53.3
N.A.
20
20
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
73.3
73.3
N.A.
40
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
0
0
0
0
0
0
50
25
34
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
9
0
34
0
0
% C
% Asp:
17
9
0
17
0
0
9
17
0
0
50
0
0
0
0
% D
% Glu:
67
9
0
67
0
0
17
9
67
9
17
25
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% F
% Gly:
9
9
9
0
0
59
42
0
0
9
0
0
0
0
0
% G
% His:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% I
% Lys:
0
0
17
0
0
0
9
0
0
0
17
0
0
0
9
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
42
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
9
9
34
0
9
9
0
42
% P
% Gln:
0
0
17
0
9
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
34
9
0
0
9
0
0
0
9
0
0
9
9
% R
% Ser:
0
25
0
0
17
17
9
0
0
9
0
0
34
17
9
% S
% Thr:
0
34
0
9
9
0
0
50
0
17
0
0
0
25
0
% T
% Val:
0
9
0
0
0
0
0
0
9
17
0
9
0
0
17
% V
% Trp:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _